Sodium ion → 5-(3-Fluorophenyl)morpholin-3-one

HRID 801169Notes

Reaction equation

HRID 801169 reaction equation

[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[Cl:1][CH2:2][C:3](=[O:4])[NH:5][CH:6]([CH2:7][OH:8])[c:9]1[cH:10][c:11]([F:15])[cH:12][cH:13][cH:14]1.[H-:17].[Na+:16]>>[CH2:2]1[C:3](=[O:4])[NH:5][CH:6]([c:9]2[cH:10][c:11]([F:15])[cH:12][cH:13][cH:14]2)[CH2:7][O:8]1

Participants

5

Reactant 4

HCID 923Sodium ion

HCID 8028Tetrahydrofuran

HCID 166653Hydride

HCID 583359312-chloro-N-(1-(3-fluorophenyl)-2-hydroxyethyl)acetamide

Product 1

HCID 583357985-(3-Fluorophenyl)morpholin-3-one

Sources & evidence

ORD record: ord-ae1cad47f32a48deb27e619a04f05874
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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