Potassium Cation → 5-Ethynylpyridin-2-amine

HRID 801281Notes

Reaction equation

HRID 801281 reaction equation
[C:14](=[O:15])([O-:16])[O-:17].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:7]1[cH:8][cH:9][c:10]([NH2:13])[n:11][cH:12]1.[CH3:25][OH:26].[K+:18].[K+:19].[OH2:27]>>[CH:5]#[C:6][c:7]1[cH:8][cH:9][c:10]([NH2:13])[n:11][cH:12]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 224828585-(2-(Trimethylsilyl)ethynyl)pyridin-2-amine

Product 1

HCID 219548275-Ethynylpyridin-2-amine

Sources & evidence

ORD record
ord-1b767eff38d941459b2e28554a384493
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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