Dichloromethane → 2-Amino-1-(3-phenyl-1,2,4-oxadiazol-5-yl)-butan-1-ol

HRID 801481Notes

Reaction equation

HRID 801481 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]([CH:10]([OH:11])[c:12]1[n:13][c:14](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[n:15][o:16]1)[CH2:23][CH3:24])([CH3:5])([CH3:6])[CH3:7].[Cl:32][CH2:33][Cl:34].[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31]>>[NH2:8][CH:9]([CH:10]([OH:11])[c:12]1[n:13][c:14](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[n:15][o:16]1)[CH2:23][CH3:24]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21962646tert-butyl N-[1-hydroxy-1-(3-phenyl-1,2,4-oxadiazol-5-yl)butan-2-yl]carbamate

Product 1

HCID 219627452-Amino-1-(3-phenyl-1,2,4-oxadiazol-5-yl)-butan-1-ol

Sources & evidence

ORD record
ord-f884fd41eac04cde82c369c67ce1fb68
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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