Water → 8-bromo-6-(morpholine-4-carbonyl)-2-morpholino-4H-chromen-4-one

HRID 801549Notes

Reaction equation

HRID 801549 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:19](=[O:20])[OH:21])[cH:5][c:6]2[c:7](=[O:18])[cH:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[o:10][c:11]12.[CH2:31]1[CH2:32][O:33][CH2:34][CH2:35][NH:36]1.[CH:22]([N:23]([CH2:24][CH3:25])[CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[Cl:38][CH2:39][Cl:40].[OH2:37]>>[Br:1][c:2]1[cH:3][c:4]([C:19](=[O:21])[N:36]2[CH2:31][CH2:32][O:33][CH2:34][CH2:35]2)[cH:5][c:6]2[c:7](=[O:18])[cH:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[o:10][c:11]12

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8083MorpholineHCID 81531DiisopropylethylamineHCID 582350518-bromo-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid

Product 1

HCID 866724148-bromo-6-(morpholine-4-carbonyl)-2-morpholino-4H-chromen-4-one

Sources & evidence

ORD record
ord-9619d9da3b094fcfae605568b00c8227
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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