Bicarbonate Ion → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

HRID 801846Notes

Reaction equation

HRID 801846 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[Na+:17].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1.[OH2:22].[OH:18][C:19](=[O:20])[O-:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][OH:15])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 3928711-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acid

Product 1

HCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-2ab8522460cf4c8cb59d75e90ef3d68a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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