Bicarbonate Ion → 5-(2-Chloroethyl)-4-methyl-1-(pyrrolidin-1-ylmethyl)pyrimido[1,6-a]indole

HRID 802083Notes

Reaction equation

HRID 802083 reaction equation
[C:25](=[O:26])([OH:27])[O-:28].[CH2:20]1[CH2:21][CH2:22][NH:23][CH2:24]1.[CH3:30][C:31]#[N:32].[Cl:1][CH2:2][CH2:3][c:4]1[c:5]2[n:6]([c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]13)[c:13]([CH2:18][Cl:19])[n:14][cH:15][c:16]2[CH3:17].[Na+:29]>>[Cl:1][CH2:2][CH2:3][c:4]1[c:5]2[n:6]([c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]13)[c:13]([CH2:18][N:23]1[CH2:22][CH2:21][CH2:20][CH2:24]1)[n:14][cH:15][c:16]2[CH3:17]

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6342AcetonitrileHCID 31268PyrrolidineHCID 127081975-(2-Chloroethyl)-1-(chloromethyl)-4-methylpyrimido[1,6-a]indole

Product 1

HCID 204850825-(2-Chloroethyl)-4-methyl-1-(pyrrolidin-1-ylmethyl)pyrimido[1,6-a]indole

Sources & evidence

ORD record
ord-0e9a0ce32bec49d2a5fab11ca9d10862
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…