Dichloromethane → 2-(4-Fluorophenyl)morpholine

HRID 802244Notes

Reaction equation

HRID 802244 reaction equation
[C:1]([O:2][C:6](=[O:3])[NH:7][CH2:8][CH:9]([OH:10])[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)([CH3:4])([CH3:5])[CH3:18].[Cl:19][CH2:20][Cl:21].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[CH2:6]1[NH:7][CH2:8][CH:9]([c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[O:10][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 16244250[2-(4-Chloro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 37492272-(4-Fluorophenyl)morpholine

Sources & evidence

ORD record
ord-a405cd9f0dce48f5b0d589c68c1593df
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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