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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 802370Generated: October 30, 2026

Dimethylformamide → 4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(3-pyrrolidin-1-ylcarbonylpropoxy)quinazoline

https://huagongshe.com/reaction/802370

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantPyrrolidineHCID 31268—
ReactantDimethylacetamideHCID 31374—
ReactantOxalyl chlorideHCID 65578—
Reactant7-(3-Carboxypropoxy)-4-(4-chloro-2-fluoroanilino)-6-methoxyquinazolineHCID 22478293—
Product4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(3-pyrrolidin-1-ylcarbonylpropoxy)quinazolineHCID 18753442—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-ea008ee222c4434a953eb4124e3fe3f6
Source noteTest data from https://doi.org/10.1039/C8SC04228D