Dimethylformamide → 4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-(3-pyrrolidin-1-ylcarbonylpropoxy)quinazoline

HRID 802370Notes

Reaction equation

[C:7](=[O:8])([OH:9])[CH2:10][CH2:11][CH2:12][O:13][c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18]([NH:24][c:25]3[c:26]([F:32])[cH:27][c:28]([Cl:31])[cH:29][cH:30]3)[n:19][cH:20][n:21][c:22]2[cH:23]1.[CH2:40]1[CH2:41][CH2:42][NH:43][CH2:44]1.[CH2:45]([Cl:46])[Cl:47].[CH3:48][N:49]([CH3:50])[C:51](=[O:52])[CH3:53].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[C:7](=[O:8])([CH2:10][CH2:11][CH2:12][O:13][c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18]([NH:24][c:25]3[c:26]([F:32])[cH:27][c:28]([Cl:31])[cH:29][cH:30]3)[n:19][cH:20][n:21][c:22]2[cH:23]1)[N:43]1[CH2:42][CH2:41][CH2:40][CH2:44]1