2,4,5-Trifluorobenzyl Bromide → 7-Iodo-1-(2,4,5-trifluorobenzyl)-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[F:13][c:14]1[c:15]([CH2:16][Br:17])[cH:18][c:19]([F:23])[c:20]([F:22])[cH:21]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[N:9]2[CH2:16][c:15]1[c:14]([F:13])[cH:21][c:20]([F:22])[c:19]([F:23])[cH:18]1Participants
3
Sources & evidence
- ORD record
- ord-e164d2dfdac941e98842e3892ae3ba3c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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