Dichloromethane → 8-(4-Fluoro-phenylethynyl)-4-[3-(4-methyl-imidazol-1-yl)-phenyl]-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:23][C:24]([CH2:25][C:26](=[O:5])[c:28]2[cH:29][c:30](-[n:34]3[cH:35][n:36][c:37]([CH3:39])[cH:38]3)[cH:31][cH:32][cH:33]2)=[O:40])[cH:10][c:11]([C:14]#[C:15][c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:12][cH:13]1)([CH3:6])([CH3:27])[CH3:41].[Cl:49][CH2:50][Cl:51].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48]>>[N:7]1=[C:26]([c:28]2[cH:29][c:30](-[n:34]3[cH:35][n:36][c:37]([CH3:39])[cH:38]3)[cH:31][cH:32][cH:33]2)[CH2:25][C:24](=[O:40])[NH:23][c:9]2[c:8]1[cH:13][cH:12][c:11]([C:14]#[C:15][c:16]1[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]1)[cH:10]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0c4e0402e1e64d08b74c7539b389f399
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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