4-(4-Fluoro-benzyloxy)-phenylamine → Hydrochloric Acid

HRID 802906Notes

Reaction equation

HRID 802906 reaction equation
[Cl:17][c:18]1[n:19][cH:20][n:21][c:22]2[cH:23][cH:24][c:25](-[c:28]3[o:29][c:30]([CH3:33])[n:31][n:32]3)[cH:26][c:27]12.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][cH:10][c:11]([NH2:12])[cH:13][cH:14]2)[cH:15][cH:16]1>>[ClH:17].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][cH:10][c:11]([NH:12][c:18]3[n:19][cH:20][n:21][c:22]4[cH:23][cH:24][c:25](-[c:28]5[o:29][c:30]([CH3:33])[n:31][n:32]5)[cH:26][c:27]34)[cH:13][cH:14]2)[cH:15][cH:16]1

Participants

4

Reactant 2

HCID 64860214-(4-Fluoro-benzyloxy)-phenylamineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 2

HCID 313Hydrochloric AcidHCID 22609767N-[4-[(4-fluorophenyl)methoxy]phenyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazolin-4-amine

Sources & evidence

ORD record
ord-a2b62707838e4033bc4c5b12200334ae
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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