HRID803075

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID735900

1-Boc-4-piperidone

C10H17NO3

结构：CC(C)[Si](C(C)C)(C(C)C)n1ccc2ccc(Cl)nc21

HCID49758945

未命名化合物

HCID178418400

未命名化合物

PRODUCTS

生成物

结构：CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(C3(O)CCN(C(=O)OC(C)(C)C)CC3)cc(Cl)nc21

HCID59006382

1,1-Dimethylethyl 4-[6-chloro-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-4-hydroxy-1-piperidinecarboxylate

C26H42ClN3O3Si

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ffc2318237de4bceb5bab412a374cc51
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[O:26]=[C:27]1[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]1>>[Cl:1][c:2]1[cH:3][c:4]([C:27]2([OH:26])[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]2)[c:5]2[c:6]([n:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2