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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803134Generated: October 27, 2026

Dimethyl Sulfoxide → 2-Fluoro-4-(3-hydroxy-2,3-dimethylpyrrolidin-1-yl)benzonitrile

https://huagongshe.com/reaction/803134

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
ReactantLithium ionHCID 28486—
Reactant2,4-DifluorobenzonitrileHCID 77545—
Reactant2,3-Dimethylpyrrolidin-3-olHCID 72325661—
Product2-Fluoro-4-(3-hydroxy-2,3-dimethylpyrrolidin-1-yl)benzonitrileHCID 74380229—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f42f1966bd404a2abb5a5da1e67e0571
Source noteTest data from https://doi.org/10.1039/C8SC04228D