Dimethyl Sulfoxide → 2-Fluoro-4-(3-hydroxy-2,3-dimethylpyrrolidin-1-yl)benzonitrile
Reaction equation
[CH3:1][CH:2]1[NH:3][CH2:4][CH2:5][C:6]1([OH:7])[CH3:8].[CH3:26][S:27]([CH3:28])=[O:29].[F:9][c:10]1[c:11]([C:12]#[N:13])[cH:14][cH:15][c:16]([F:18])[cH:17]1.[Li+:19].[Li+:20].[O-:21][C:22](=[O:23])[O-:24].[OH2:25]>>[CH3:1][CH:2]1[N:3]([c:16]2[cH:15][cH:14][c:11]([C:12]#[N:13])[c:10]([F:9])[cH:17]2)[CH2:4][CH2:5][C:6]1([OH:7])[CH3:8]Participants
7
Sources & evidence
- ORD record
- ord-f42f1966bd404a2abb5a5da1e67e0571
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…