1,2-Dichloroethane → 1-(2,4-dimethoxyphenyl)-N-(1,2,3-thiadiazol-4-ylmethyl)methanamine

HRID 803312Notes

Reaction equation

HRID 803312 reaction equation
[C:20]([O:21][BH-:22]([O:23][C:24](=[O:25])[CH3:26])[O:27][C:28](=[O:29])[CH3:30])(=[O:31])[CH3:32].[C:34](=[O:35])([O-:36])[OH:37].[CH3:8][O:9][c:10]1[c:11]([CH2:12][NH2:13])[cH:14][cH:15][c:16]([O:18][CH3:19])[cH:17]1.[Cl:39][CH2:40][CH2:41][Cl:42].[Cl:43][CH2:44][Cl:45].[Na+:33].[Na+:38].[s:1]1[n:2][n:3][c:4]([CH:6]=[O:7])[cH:5]1>>[s:1]1[n:2][n:3][c:4]([CH2:6][NH:13][CH2:12][c:11]2[c:10]([O:9][CH3:8])[cH:17][c:16]([O:18][CH3:19])[cH:15][cH:14]2)[cH:5]1

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 5972502,4-DimethoxybenzylamineHCID 2724942TriacetoxyborohydrideHCID 27372711,2,3-Thiadiazole-4-carbaldehyde

Product 1

HCID 610345781-(2,4-dimethoxyphenyl)-N-(1,2,3-thiadiazol-4-ylmethyl)methanamine

Sources & evidence

ORD record
ord-8af9945435f6438cbd7feee3e8dba6b8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…