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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80332Generated: October 28, 2026

Phenethylamine → 3-(2-Phenylethylamino)methylenedihydrofuran-2-one

https://huagongshe.com/reaction/80332

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
ReactantHCID 66988753HCID 66988753—
Product3-(2-Phenylethylamino)methylenedihydrofuran-2-oneHCID 6698865375%

Reaction Steps

Using 3-hydroxymethylenedihydrofuran-2-one sodium salt (50 mmol) and 2-phenylethylamine (55 mmol) and proceeding according to the abovementioned method A1, 3-(2-phenylethylamino)methylenedihydrofuran-2-one (8.14 g, efficiency: 75%) is produced in the form of a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846125B2
Source datasetuspto-grants-2014_09
ORD IDord-df8ce6a561ad4516a4a1bb34bb961ffd
Source noteuspto-grants-2014_09