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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 803326Generated: November 1, 2026

Tetrahydrofuran → 8-Methyl-6-(4-trifluoromethyl-phenyl)-3-trimethylsilanylethynyl-imidazo[1,2-a]pyridine

https://huagongshe.com/reaction/803326

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant3-Iodo-8-methyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridineHCID 67000127—
Product8-Methyl-6-(4-trifluoromethyl-phenyl)-3-trimethylsilanylethynyl-imidazo[1,2-a]pyridineHCID 67000973—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d805a3eb507d41c2baf58298665977f0
Source noteTest data from https://doi.org/10.1039/C8SC04228D