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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80334Generated: October 29, 2026

4-Chlorobenzylamine → 3-(4-Chlorobenzylamino)methylenedihydrofuran-2-one

https://huagongshe.com/reaction/80334

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantHCID 66988753HCID 66988753—
Product3-(4-Chlorobenzylamino)methylenedihydrofuran-2-oneHCID 6698843073%

Reaction Steps

Using 3-hydroxymethylenedihydrofuran-2-one sodium salt (10 mmol) and 4-chlorobenzylamine (11 mmol) and proceeding according to the abovementioned method A2, 3-(4-chlorobenzylamino)methylenedihydrofuran-2-one (1.5 g, 73%) is produced in the form of a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846125B2
Source datasetuspto-grants-2014_09
ORD IDord-bbcd5cd95dcc48e49829a5a866f02726
Source noteuspto-grants-2014_09