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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80335Generated: October 29, 2026

4-Methoxybenzylamine → 3-(4-Methoxybenzylamino)methylenedihydrofuran-2-one

https://huagongshe.com/reaction/80335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
ReactantHCID 66988753HCID 66988753—
Product3-(4-Methoxybenzylamino)methylenedihydrofuran-2-oneHCID 6698821928%

Reaction Steps

Using 3-hydroxymethylenedihydrofuran-2-one sodium salt (50 mmol) and 4-methoxybenzylamine (55 mmol) and proceeding according to the abovementioned method A1, 3-(4-methoxybenzylamino)methylenedihydrofuran-2-one (2.9 g, efficiency: 28%) is produced in the form of a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846125B2
Source datasetuspto-grants-2014_09
ORD IDord-5525dac6a90d456b913a69fa3d2b58c1
Source noteuspto-grants-2014_09