Methanol → Methyl 4-bromo-3-fluorobenzoate

HRID 803420Notes

Reaction equation

[Br:1][c:2]1[c:3]([F:11])[cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[CH3:12][Si:13]([CH:14]=[N+:15]=[N-:16])([CH3:17])[CH3:18].[CH3:19][OH:20].[Cl:21][CH2:22][Cl:23]>>[Br:1][c:2]1[c:3]([F:11])[cH:4][c:5]([C:6](=[O:7])[O:8][CH3:12])[cH:9][cH:10]1

Participants

Reactant 4

HCID 887Methanol

HCID 6344Dichloromethane

HCID 167693Trimethylsilyldiazomethane

HCID 27733414-Bromo-3-fluorobenzoic acid

Product 1

HCID 21951878Methyl 4-bromo-3-fluorobenzoate

Sources & evidence

ORD record: ord-b3398c696c4a4cb897fd55bbeaaba0b5
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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