Dichloromethane → 1-(5-Trifluoromethylpyridin-2-yl)azetidin-3-ylamine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][N:10]([c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:22].[Cl:30][CH2:31][Cl:32].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH2:7][CH:8]1[CH2:9][N:10]([c:12]2[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[CH2:11]1Participants
4
Sources & evidence
- ORD record
- ord-cf9f6854db3c4e52b3ffd4c9cbb3fb1a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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