Phosphorus oxychloride → 5-benzyl-4-chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine
Reaction equation
[NH2:1][c:2]1[nH:3][c:4](=[O:18])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][n:10]2[CH2:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[P:19]([Cl:20])([Cl:21])([Cl:22])=[O:23]>>[NH2:1][c:2]1[n:3][c:4]([Cl:21])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][n:10]2[CH2:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1Participants
3
Sources & evidence
- ORD record
- ord-a433e581d3ea4c3ea864402c51f2115b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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