Dichloromethane → N-methyl-1-(5-(thiophen-2-yl)tetrazolo[1,5-a]pyrazin-8-yl)azetidin-3-amine
Reaction equation
[CH3:1][N:2]([C:3](=[O:4])[O:5][C:6]([CH3:7])([CH3:8])[CH3:9])[CH:10]1[CH2:11][N:12]([c:14]2[c:15]3[n:16]([c:17](-[c:20]4[s:21][cH:22][cH:23][cH:24]4)[cH:18][n:19]2)[n:25][n:26][n:27]3)[CH2:13]1.[Cl:35][CH2:36][Cl:37].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[CH3:1][NH:2][CH:10]1[CH2:11][N:12]([c:14]2[c:15]3[n:16]([c:17](-[c:20]4[s:21][cH:22][cH:23][cH:24]4)[cH:18][n:19]2)[n:25][n:26][n:27]3)[CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-ab20dea3ae0347bca563386fc424d5b6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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