1,2-Dichloroethane → tert-Butyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate

HRID 803703Notes

Reaction equation

HRID 803703 reaction equation
[C:23]([O:24][BH-:25]([O:26][C:27](=[O:28])[CH3:29])[O:30][C:31](=[O:32])[CH3:33])(=[O:34])[CH3:35].[Cl:37][CH2:38][CH2:39][Cl:40].[Na+:36].[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1.[n:15]1[c:16]([NH2:22])[c:17]([NH2:21])[cH:18][cH:19][cH:20]1>>[CH:2]1([NH:21][c:17]2[c:16]([NH2:22])[n:15][cH:20][cH:19][cH:18]2)[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 923Sodium ionHCID 99562,3-DiaminopyridineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 2724942Triacetoxyborohydride

Product 1

HCID 22293217tert-Butyl 4-[(2-aminopyridin-3-yl)amino]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-d58202897086421680d4a8c0d5adb2cd
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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