Benzene → 2-Fluoro-4-methylsulfonylphenol

HRID 803777Notes

Reaction equation

HRID 803777 reaction equation
[Br:6][c:7]1[cH:8][c:9]([F:14])[c:10]([OH:13])[cH:11][cH:12]1.[CH3:15][NH:16][CH2:17][CH2:18][NH:19][CH3:20].[CH3:1][S:2](=[O:3])[OH:4].[CH3:36][S:37]([CH3:38])=[O:39].[Cu+:35].[F:27][C:28]([F:29])([F:30])[S:31]([O-:32])(=[O:33])=[O:34].[Na:5].[cH:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:7]1[cH:8][c:9]([F:14])[c:10]([OH:13])[cH:11][cH:12]1

Participants

9

Reactant 8

HCID 241BenzeneHCID 679Dimethyl SulfoxideHCID 8070N,N'-DimethylethylenediamineHCID 87251Methanesulfinic acidHCID 104815Copper(1+)HCID 27249814-Bromo-2-fluorophenolHCID 2758875TrifluoromethanesulfonateHCID 5360545Sodium

Product 1

HCID 161288422-Fluoro-4-methylsulfonylphenol

Sources & evidence

ORD record
ord-51e0864dc6ed4ac2a4ee98d0bdb72779
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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