Hydrochloric Acid → Methyl 4-(hydroxymethyl)piperidine-4-carboxylate

HRID 803785Notes

Reaction equation

[CH3:21][OH:22].[ClH:20].[OH:1][CH2:2][C:3]1([C:16](=[O:17])[O:18][CH3:19])[CH2:4][CH2:5][N:6]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[CH2:7][CH2:8]1>>[OH:1][CH2:2][C:3]1([C:16](=[O:17])[O:18][CH3:19])[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 579202781-tert-Butyl 4-methyl 4-(hydroxymethyl)piperidine-1,4-dicarboxylate

Product 1

HCID 57920285Methyl 4-(hydroxymethyl)piperidine-4-carboxylate

Sources & evidence

ORD record: ord-6949428d51fa49f4b6ec88a2ce8f3a54
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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