Diethyl Carbonate → 1-[2-(Tetrahydro-2-oxo-1,3-oxazin-3-yl)ethyl]-3-phenylurea

HRID 803901Notes

Reaction equation

HRID 803901 reaction equation
[C:36](=[O:37])([O:38][CH2:39][CH3:40])[O:41][CH2:42][CH3:43].[Cl:1][CH2:2][CH2:3][CH2:4][OH:5].[NH2:6][CH2:7][CH2:8][NH:9][C:10]([NH:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)=[O:18].[OH:19][CH2:20][CH2:21][CH2:22][NH:23][CH2:24][CH2:25][NH:26][C:27](=[O:28])[NH:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[C:4]1(=[O:5])[O:19][CH2:20][CH2:21][CH2:22][N:23]1[CH2:24][CH2:25][NH:26][C:27](=[O:28])[NH:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1

Participants

5

Reactant 4

HCID 7766Diethyl CarbonateHCID 123133-Chloro-1-propanolHCID 12681829N-(2-Aminoethyl)-N'-phenylureaHCID 214274161-[2-(3-Hydroxypropylamino)ethyl]-3-phenylurea

Product 1

HCID 214274141-[2-(Tetrahydro-2-oxo-1,3-oxazin-3-yl)ethyl]-3-phenylurea

Sources & evidence

ORD record
ord-82e7c5476b6d4ad6a67e2b9e1acc864f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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