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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 804036Generated: October 30, 2026

4-(Difluoromethoxy)benzyl Bromide → 2-(3-(4-(difluoromethoxy)benzyl)-2-oxopyrrolidin-1-yl)-N-(4-fluorobenzyl)-4-methylthiazole-5-carboxamide

https://huagongshe.com/reaction/804036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Difluoromethoxy)benzyl BromideHCID 2737001—
Reactant4-(3-ethylisoxazol-5-yl)-N-[3-(trifluoromethyl)phenyl]thiophene-2-sulfonamideHCID 16954475—
Product2-(3-(4-(difluoromethoxy)benzyl)-2-oxopyrrolidin-1-yl)-N-(4-fluorobenzyl)-4-methylthiazole-5-carboxamideHCID 24801507—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c61ec8b5919a4685a3900c37f463526e
Source noteTest data from https://doi.org/10.1039/C8SC04228D