Dichloromethane → 3-Propyl-6-{3-[(2,4,6-trimethyl-benzylamino)-methyl]-phenoxy}-3,4-dihydro-quinazolin-2-ylamine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][C:8]1=[N:9][c:10]2[cH:11][cH:12][c:13]([O:21][c:22]3[cH:23][c:24]([CH2:28][NH:29][CH2:30][c:31]4[c:32]([CH3:39])[cH:33][c:34]([CH3:38])[cH:35][c:36]4[CH3:37])[cH:25][cH:26][cH:27]3)[cH:14][c:15]2[CH2:16][N:17]1[CH2:18][CH2:19][CH3:20])([CH3:5])([CH3:6])[CH3:40].[Cl:48][CH2:49][Cl:50].[OH:41][C:42]([C:43]([F:44])([F:45])[F:46])=[O:47]>>[NH2:7][C:8]1=[N:9][c:10]2[cH:11][cH:12][c:13]([O:21][c:22]3[cH:23][c:24]([CH2:28][NH:29][CH2:30][c:31]4[c:32]([CH3:39])[cH:33][c:34]([CH3:38])[cH:35][c:36]4[CH3:37])[cH:25][cH:26][cH:27]3)[cH:14][c:15]2[CH2:16][N:17]1[CH2:18][CH2:19][CH3:20]Participants
4
Sources & evidence
- ORD record
- ord-2e27181611f84532a97ca2f57fdfea06
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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