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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80412Generated: October 29, 2026

2-(Trifluoromethylthio)ethyl Trifluoromethanesulfonate → 4-Trifluoromethylsulfanyl-2-(3,3,3-trifluoro-2-methyl-2-trifluoromethyl-propane-1-sulfonyl)-butyronitrile

https://huagongshe.com/reaction/80412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethylthio)ethyl TrifluoromethanesulfonateHCID 25242028—
Reactant(3,3,3-Trifluoro-2-methyl-2-trifluoromethyl-propane-1-sulfonyl)-acetonitrileHCID 86673277—
Product4-Trifluoromethylsulfanyl-2-(3,3,3-trifluoro-2-methyl-2-trifluoromethyl-propane-1-sulfonyl)-butyronitrileHCID 86673276—

Reaction Steps

Compound II-28 was prepared from (3,3,3-trifluoro-2-methyl-2-trifluoromethyl-propane-1-sulfonyl)-acetonitrile and trifluoro-methanesulfonic acid 2-trifluoromethylsulfanyl-ethyl ester as described for compound II-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846569B2
Source datasetuspto-grants-2014_09
ORD IDord-dc3cb636aada45639f626529edb5439d
Source noteuspto-grants-2014_09