Dichloromethane → 1-{2-[4-(2,6-Dichlorobenzyl)piperazin-1-yl]-2-oxoethyl}-3,3-diphenylpyrrolidin-2-one

HRID 804128Notes

Reaction equation

HRID 804128 reaction equation
[CH:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH2:43][CH3:44])([CH3:45])[CH3:46].[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[c:11]([Cl:15])[cH:12][cH:13][cH:14]1.[Cl:47][CH2:48][Cl:49].[O:16]=[C:17]1[N:18]([CH2:34][C:35](=[O:36])[OH:37])[CH2:19][CH2:20][C:21]1([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][N:8]([C:35]([CH2:34][N:18]3[C:17](=[O:16])[C:21]([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)([c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[CH2:20][CH2:19]3)=[O:36])[CH2:9][CH2:10]2)[c:11]([Cl:15])[cH:12][cH:13][cH:14]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 7707961-(2,6-Dichlorobenzyl)piperazineHCID 673590132-(2-Oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid

Product 1

HCID 452743081-{2-[4-(2,6-Dichlorobenzyl)piperazin-1-yl]-2-oxoethyl}-3,3-diphenylpyrrolidin-2-one

Sources & evidence

ORD record
ord-a1391e3ae9534eff991bf3d670620e29
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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