Dichloromethane → 4-(4-Chloro-2-methylbenzoyl)piperazin-2-one

HRID 804193Notes

Reaction equation

HRID 804193 reaction equation
[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cl:15][c:16]1[cH:17][c:18]([CH3:25])[c:19]([C:20](=[O:21])[Cl:22])[cH:23][cH:24]1.[Cl:26][CH2:27][Cl:28].[NH:1]1[C:2](=[O:7])[CH2:3][NH:4][CH2:5][CH2:6]1>>[NH:1]1[C:2](=[O:7])[CH2:3][N:4]([C:20]([c:19]2[c:18]([CH3:25])[cH:17][c:16]([Cl:15])[cH:24][cH:23]2)=[O:21])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 231360Piperazin-2-oneHCID 128464844-Chloro-2-methylbenzoyl chloride

Product 1

HCID 665987464-(4-Chloro-2-methylbenzoyl)piperazin-2-one

Sources & evidence

ORD record
ord-1f856390385b4e879fe71f5d6ec7939b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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