Bicarbonate Ion → 2-(2-(4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethoxy)ethyl benzoate

HRID 804217Notes

Reaction equation

HRID 804217 reaction equation
[C:11](=[O:12])([O-:13])[O-:14].[C:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)(=[O:24])[O:25][CH2:26][CH2:27][O:28][CH2:29][CH2:30][I:31].[C:32](=[O:33])([O-:34])[OH:35].[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][nH:10]2.[Cs+:15].[Cs+:16].[Na+:36]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH2:30][CH2:29][O:28][CH2:27][CH2:26][O:25][C:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)=[O:24]

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 53706954-chloro-5H-pyrrolo[3,2-d]pyrimidineHCID 213618682-(2-Iodoethoxy)ethyl benzoate

Product 1

HCID 568508032-(2-(4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethoxy)ethyl benzoate

Sources & evidence

ORD record
ord-bc4264422db646f7aaab245706528375
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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