1-Butanol → Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

HRID 804335Notes

Reaction equation

HRID 804335 reaction equation
[CH2:31]([OH:32])[CH2:33][CH2:34][CH3:35].[CH:22]([N:23]([CH2:24][CH3:25])[CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[Cl:14][c:15]1[n:16][c:17]([Cl:21])[cH:18][n:19][cH:20]1.[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([c:17]2[n:16][c:15]([Cl:14])[cH:20][n:19][cH:18]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 2631-ButanolHCID 785042,6-DichloropyrazineHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 18186946Tert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-f3aa30fa4bb84f2492428e448f0e3e2d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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