Dimethylformamide → 2-Amino-3,5-dimorpholinopyrazine

HRID 804434Notes

Reaction equation

[CH2:15]1[CH2:16][O:17][CH2:18][CH2:19][NH:20]1.[CH3:21][N:22]([CH3:23])[CH:24]=[O:25].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:14])[n:6][c:7]1[N:8]1[CH2:9][CH2:10][O:11][CH2:12][CH2:13]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([N:20]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:6][c:7]1[N:8]1[CH2:9][CH2:10][O:11][CH2:12][CH2:13]1

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 8083Morpholine

HCID 167404415-Bromo-3-morpholinopyrazin-2-amine

Product 1

HCID 205289312-Amino-3,5-dimorpholinopyrazine

Sources & evidence

ORD record: ord-d5d8be514bda428395d680470a81bb65
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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