Hydrochloric Acid → N-[1-(4-acetamidocyclohexanecarbonyl)-3-(4-chloro-3-methylphenyl)piperidin-4-yl]-3-bromo-N-methyl-5-(trifluoromethyl)benzamide

HRID 804514Notes

Reaction equation

HRID 804514 reaction equation
[Br:2][c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[CH:10]2[CH:11]([c:16]3[cH:17][c:18]([CH3:23])[c:19]([Cl:22])[cH:20][cH:21]3)[CH2:12][NH:13][CH2:14][CH2:15]2)[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1.[C:31]([CH3:32])(=[O:33])[NH:34][CH:35]1[CH2:36][CH2:37][CH:38]([C:41](=[O:42])[OH:43])[CH2:39][CH2:40]1.[ClH:1]>>[Br:2][c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[CH:10]2[CH:11]([c:16]3[cH:17][c:18]([CH3:23])[c:19]([Cl:22])[cH:20][cH:21]3)[CH2:12][N:13]([C:41]([CH:38]3[CH2:37][CH2:36][CH:35]([NH:34][C:31]([CH3:32])=[O:33])[CH2:40][CH2:39]3)=[O:42])[CH2:14][CH2:15]2)[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 147882144-Acetamidocyclohexane-1-carboxylic acidHCID 876263413-bromo-N-[3-(4-chloro-3-methylphenyl)piperidin-4-yl]-N-methyl-5-(trifluoromethyl)benzamide

Product 1

HCID 68935588N-[1-(4-acetamidocyclohexanecarbonyl)-3-(4-chloro-3-methylphenyl)piperidin-4-yl]-3-bromo-N-methyl-5-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-aa1aae795c764b97a68cef80b8e83f7d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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