Dichloromethane → tert-butyl 4-[(5R,7R)-7-hydroxy-5-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl]piperazine-1-carboxylate
Reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:8][CH:9]1[CH2:10][C:11](=[O:31])[c:12]2[n:13][cH:14][n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]3)[c:17]21.[Cl:56][CH2:57][Cl:58].[OH:32][CH:33]1[c:34]2[n:35][cH:36][n:37][c:38]([N:39]3[CH2:40][CH2:41][N:42]([C:43]([O:44][C:45]([CH3:46])([CH3:47])[CH3:48])=[O:49])[CH2:50][CH2:51]3)[c:52]2[CH:53]([CH3:54])[CH2:55]1>>[CH3:8][CH:9]1[CH2:10][CH:11]([OH:31])[c:12]2[n:13][cH:14][n:15][c:16]([N:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]3)[c:17]21Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f11357f584b44983b5851f2446c253ff
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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