Diethyl cyanophosphonate → 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-N-[2-(isopropylamino)ethyl]-1-methyl-1H-pyrrole-3-carboxamide
Reaction equation
[C:44]([P:45](=[O:46])([O:47][CH2:48][CH3:49])[O:50][CH2:51][CH3:52])#[N:53].[CH:37]([CH3:38])([CH3:39])[NH:40][CH2:41][CH2:42][NH2:43].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH2:11][n:12]3[n:13][c:14]4[n:15]([CH2:33][CH:34]([CH3:35])[CH3:36])[c:16](=[O:32])[n:17]([CH3:31])[c:18](=[O:30])[c:19]4[c:20]3-[c:21]3[cH:22][c:23]([C:27](=[O:28])[OH:29])[cH:24][n:25]3[CH3:26])[cH:6][nH:7][c:8]2[cH:9][cH:10]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([CH2:11][n:12]3[n:13][c:14]4[n:15]([CH2:33][CH:34]([CH3:35])[CH3:36])[c:16](=[O:32])[n:17]([CH3:31])[c:18](=[O:30])[c:19]4[c:20]3-[c:21]3[cH:22][c:23]([C:27](=[O:29])[NH:43][CH2:42][CH2:41][NH:40][CH:37]([CH3:38])[CH3:39])[cH:24][n:25]3[CH3:26])[cH:6][nH:7][c:8]2[cH:9][cH:10]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-fb95ea32ff3645cb9dc00319300efc20
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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