Hydrogen Bromide → 1-[[[4-[2-[4-(4-Morpholinyl)-1-piperazinyl]-4-thiazolyl]phenyl]carbonyl]amino]cyclohexanecarboxylic acid methyl ester

HRID 804593Notes

Reaction equation

HRID 804593 reaction equation
[BrH:1].[CH3:28][O:29][C:30](=[O:31])[C:32]1([NH2:38])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]1.[O:2]1[CH2:3][CH2:4][N:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[s:15][cH:16][c:17](-[c:19]4[cH:20][cH:21][c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27]4)[n:18]3)[CH2:12][CH2:13]2)[CH2:6][CH2:7]1>>[O:2]1[CH2:3][CH2:4][N:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[s:15][cH:16][c:17](-[c:19]4[cH:20][cH:21][c:22]([C:23](=[O:24])[NH:38][C:32]5([C:30]([O:29][CH3:28])=[O:31])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]5)[cH:26][cH:27]4)[n:18]3)[CH2:12][CH2:13]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 4048819Methyl 1-aminocyclohexanoateHCID 671817724-[2-(4-Morpholin-4-ylpiperazin-1-yl)-1,3-thiazol-4-yl]benzoic acid

Product 1

HCID 671824901-[[[4-[2-[4-(4-Morpholinyl)-1-piperazinyl]-4-thiazolyl]phenyl]carbonyl]amino]cyclohexanecarboxylic acid methyl ester

Sources & evidence

ORD record
ord-165fd66015a84653a9599a0f63732aa2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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