Acetic Acid → 1-(4-Amino-5-fluoropyridin-2-yl)-8-chloro-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Reaction equation
[CH3:29][C:30](=[O:31])[OH:32].[ClH:1].[NH2:2][c:3]1[cH:4][c:5](-[n:10]2[cH:11][c:12]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[c:13](=[O:23])[c:14]3[cH:15][c:16]([F:22])[c:17]([F:21])[c:18]([Cl:20])[c:19]23)[n:6][cH:7][c:8]1[F:9]>>[NH2:2][c:3]1[cH:4][c:5](-[n:10]2[cH:11][c:12]([C:24](=[O:25])[OH:26])[c:13](=[O:23])[c:14]3[cH:15][c:16]([F:22])[c:17]([F:21])[c:18]([Cl:20])[c:19]23)[n:6][cH:7][c:8]1[F:9]Participants
4
Sources & evidence
- ORD record
- ord-303dffd2360d46f886da44d894ac54dc
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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