Hydrochloric Acid → 2-((2-(4-(Oxazol-5-yl)phenylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)(phenyl)amino)ethanol

HRID 804676Notes

Reaction equation

HRID 804676 reaction equation
[CH3:42][OH:43].[ClH:1].[OH2:41].[OH:2][CH2:3][CH2:4][N:5]([c:6]1[c:7]2[c:8]([n:9][c:10]([NH:12][c:13]3[cH:14][cH:15][c:16](-[c:19]4[cH:20][n:21][cH:22][o:23]4)[cH:17][cH:18]3)[n:11]1)[CH2:24][CH2:25][N:26]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:27]2)[c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[OH:2][CH2:3][CH2:4][N:5]([c:6]1[c:7]2[c:8]([n:9][c:10]([NH:12][c:13]3[cH:14][cH:15][c:16](-[c:19]4[cH:20][n:21][cH:22][o:23]4)[cH:17][cH:18]3)[n:11]1)[CH2:24][CH2:25][NH:26][CH2:27]2)[c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 962WaterHCID 59333719tert-butyl 4-((2-hydroxyethyl)(phenyl)amino)-2-(4-(oxazol-5-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Product 1

HCID 462000502-((2-(4-(Oxazol-5-yl)phenylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)(phenyl)amino)ethanol

Sources & evidence

ORD record
ord-5660f23dd0bd492b97a1b29638fb5308
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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