Hydrochloric Acid → N-{1-[6-(Acetylamino)-2-(methylsulfanyl)-4-pyrimidinyl]-4-piperidinyl}-3,4-dichloro-5-methyl-1H-pyrrole-2-carboxamide

HRID 804746Notes

Reaction equation

HRID 804746 reaction equation
[Cl:21][c:22]1[c:23]([C:29](=[O:30])[NH:31][CH:32]2[CH2:33][CH2:34][N:35]([c:36]3[cH:37][c:38](-[c:39]4[n:40][cH:41][o:42][n:43]4)[cH:44][c:45]([Cl:46])[n:47]3)[CH2:48][CH2:49]2)[nH:24][c:25]([CH3:28])[c:26]1[Cl:27].[ClH:1].[NH2:2][CH:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][c:11]([NH:17][C:18]([CH3:19])=[O:20])[n:12][c:13]([S:15][CH3:16])[n:14]2)[CH2:7][CH2:8]1>>[NH:2]([CH:3]1[CH2:4][CH2:5][N:6]([c:9]2[cH:10][c:11]([NH:17][C:18]([CH3:19])=[O:20])[n:12][c:13]([S:15][CH3:16])[n:14]2)[CH2:7][CH2:8]1)[C:29]([c:23]1[c:22]([Cl:21])[c:26]([Cl:27])[c:25]([CH3:28])[nH:24]1)=[O:30]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 68582444N-[6-(4-aminopiperidin-1-yl)-2-methylsulfanylpyrimidin-4-yl]acetamideHCID 866083163,4-Dichloro-N-{1-[6-chloro-4-(1,2,4-oxadiazol-3-yl)-2-pyridinyl]-4-piperidinyl}-5-methyl-1H-pyrrole-2-carboxamide

Product 1

HCID 68580101N-{1-[6-(Acetylamino)-2-(methylsulfanyl)-4-pyrimidinyl]-4-piperidinyl}-3,4-dichloro-5-methyl-1H-pyrrole-2-carboxamide

Sources & evidence

ORD record
ord-b5df97b36509485fae52671dca632b3e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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