Sodium ion → 1-Bromo-3-(2,2,2-trifluoroethoxy)benzene

HRID 804771Notes

Reaction equation

HRID 804771 reaction equation
[Br:17][c:18]1[cH:19][c:20]([OH:24])[cH:21][cH:22][cH:23]1.[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:12][C:13]([F:14])([F:15])[F:16])(=[O:8])=[O:9])[cH:10][cH:11]1.[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[Na+:26].[OH-:25]>>[CH2:12]([C:13]([F:14])([F:15])[F:16])[O:24][c:20]1[cH:19][c:18]([Br:17])[cH:23][cH:22][cH:21]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 961HydroxideHCID 6228DimethylformamideHCID 115633-BromophenolHCID 67942Ethanol, 2,2,2-trifluoro-, 1-(4-methylbenzenesulfonate)

Product 1

HCID 247053311-Bromo-3-(2,2,2-trifluoroethoxy)benzene

Sources & evidence

ORD record
ord-c68b175f0aaa4005855f2880a949ea79
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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