Dichloromethane → 3-(2-Thiazolyl)piperidine

HRID 805040Notes

Reaction equation

HRID 805040 reaction equation
[Cl:19][CH2:20][Cl:21].[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28].[s:1]1[c:2]([CH:6]2[CH2:7][N:8]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:9][CH2:10][CH2:11]2)[n:3][cH:4][cH:5]1>>[s:1]1[c:2]([CH:6]2[CH2:7][NH:8][CH2:9][CH2:10][CH2:11]2)[n:3][cH:4][cH:5]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 534852273-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

Product 1

HCID 242618023-(2-Thiazolyl)piperidine

Sources & evidence

ORD record
ord-d75f3a3186f749ae81fcb26c605a6703
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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