Potassium Cation → Tert-butyl 4-(2-chloro-4-cyanophenyl)piperazine-1-carboxylate

HRID 805140Notes

Reaction equation

HRID 805140 reaction equation
[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[Cl:14][c:15]1[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21][c:22]1[F:23].[K+:24].[K+:25].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[O-:26][C:27]([O-:28])=[O:29]>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([c:22]2[c:15]([Cl:14])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 143452tert-Butyl piperazine-1-carboxylateHCID 1455253-Chloro-4-fluorobenzonitrile

Product 1

HCID 58324393Tert-butyl 4-(2-chloro-4-cyanophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-869d4c4e467640a88d1f559648dc635c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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