Methanol → tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

HRID 805164Notes

Reaction equation

HRID 805164 reaction equation
[CH3:23][OH:24].[CH3:25][CH2:26][O:27][C:28]([CH3:29])=[O:30].[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([N:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1>>[NH2:1][c:4]1[cH:5][cH:6][c:7]([N:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8857Ethyl AcetateHCID 33806961-Boc-4-(4-Nitrophenyl)piperazine

Product 1

HCID 11011301tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-3dafc29eeb064a5d95a3ee94e944bd7d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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