Acetic Acid → 9-fluoro-6-(1-hydroxy-1-methylethyl)benzo[c]-1,6-naphthyridin-1(2H)-one
Reaction equation
[BrH:25].[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][c:6]1[c:7]2[c:8]3[c:9]([c:10]([C:16]([CH3:17])([CH3:18])[OH:19])[n:11][c:12]2[cH:13][cH:14][n:15]1)[cH:20][cH:21][c:22]([F:24])[cH:23]3.[CH3:26][C:27](=[O:28])[OH:29]>>[O:5]=[c:6]1[c:7]2[c:8]3[c:9]([c:10]([C:16]([CH3:17])([CH3:18])[OH:19])[n:11][c:12]2[cH:13][cH:14][nH:15]1)[cH:20][cH:21][c:22]([F:24])[cH:23]3Participants
4
Sources & evidence
- ORD record
- ord-997f125fd308428795717a0a503589ca
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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