HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 3-Benzyl-7-oxo-6,7-dihydro-5h-pyrido[3,4-d][2]benzazepin-3-ium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | HCID 59548516 | HCID 59548516 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Benzyl-7-oxo-6,7-dihydro-5h-pyrido[3,4-d][2]benzazepin-3-ium bromide | HCID 67247773 | — |
Reaction Steps
A mixture of Example 180D (24.6 g, 0.117 mol) and benzyl bromide (40.1 g, 0.234 mol) in 200 mL of ethanol was stirred at reflux overnight. After cooling with an ice-water bath, the solid was collected by filtration and washed with ethanol to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846663B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-be39230d9547409f9ab4da7497a16110 |
| Source note | uspto-grants-2014_09 |