Hydrochloric Acid → N-[3-(4-Piperidinyl)phenyl]propanamide

HRID 805333Notes

Reaction equation

HRID 805333 reaction equation
[C:1]([CH2:2][CH3:3])(=[O:4])[NH:5][c:6]1[cH:7][c:8]([CH:12]2[CH2:13][CH2:14][N:15]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:16][CH2:17]2)[cH:9][cH:10][cH:11]1.[ClH:25].[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1>>[C:1]([CH2:2][CH3:3])(=[O:4])[NH:5][c:6]1[cH:7][c:8]([CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:9][cH:10][cH:11]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 22049473Tert-butyl 4-[3-(propionylamino)phenyl]-1-piperidinecarboxylate

Product 1

HCID 22048836N-[3-(4-Piperidinyl)phenyl]propanamide

Sources & evidence

ORD record
ord-a9ea42fc30ad4a7ba091773a3d4d58fb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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